London Tene was last seen around 2 p.m. near Stanwood Street, police said, adding that she may be in the New York area.
She is described as a white young woman with dark brown hair, standing at 5 feet 3 inches, and weighing about 110 pounds.
London was last seen wearing a baby blue Champion hoodie, gray leggings, and a black/white Champion slides, according to police.
Anyone with information on her whereabouts is asked to contact 911 or Boston police at 617-343-4275.
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